Etomidate (USAN, INN, BAN; marketed as Amidate) is a short-acting intravenous anaesthetic agent used for the induction of general anaesthesia and sedation for short procedures such as reduction of dislocated joints, tracheal intubation, cardioversion and electroconvulsive therapy. It was developed at Janssen Pharmaceutica in 1964 and was introduced as an intravenous agent in 1972 in Europe and in 1983 in the United States. The most common side effects include venous pain on injection and skeletal muscle movements.

ETOMIDATE is an intravenous sedative-hypnotic agent that is highly valued for its ability to maintain hemodynamic stability even in elderly or critically ill patients.

Etomidate is the most commonly used induction agent for rapid sequence intubation. It is a nonbarbiturate-sedative, which depresses central nervous system function by activating gamma-aminobutyric acid (GABA) receptors.

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