• 4-PRO-DMT

4-PRO-DMT .FUMARATE:

Synonyms: O-Propionylpsilocin
IUPAC NAME: [3-[2-(dimethylamino)ethyl]-1H-indol-4-yl] propanoate
Chemical formula: C15H20N2O2
Molar mass: 260.337 g·mol−1
CAS Number: 1373882-11-1

4-Propionoxy-N,N-dimethyltryptamine (4-PrO-DMT, or O-Propionylpsilocin) is a synthetic psychedelic drug from the tryptamine family with psychedelic effects, and is believed to act as a prodrug for psilocin. It produces a head-twitch response in mice. It has been sold online as a designer drug since May 2019. It was first identified as a new psychoactive substance in Sweden, in July 2019. A number of related derivatives have been synthesized as prodrugs of psilocin for medical applications.

This product is intended for laboratory research purposes only and are not to be used for any other purposes.
This product can't be shipped to Australia.


report:

In the past few weeks I've gotten to know 4-PrO-DMT, and felt compelled to help chisel out this interesting and noteworthy cousin of psilocybin - there are a handful of reports on Reddit and Bluelight between 2019 up thru 2024 - and I wanted to add what bits I could to the discussion.

Addressing the "Is this a pro-drug for psilocybin & does it produce distinct effects?" question - for me, 4-PrO-DMT, magic mushrooms and 4-AcO-DMT all produce similar but *distinct* states. All three have me bearing witness to a complex, intelligent process / agenda. 4-PrO-DMT seems more detached - less beneficent than 4-AcO-DMT - but not less intelligent, aware or capable. Admittedly - until I am able to correctly identify these three substances predictably in a double-blind scenario, their perceived differences are my untested and biased opinion.

What is clear to me - after six trials (7mg, 12mg, 20mg, 25mg, 30mg, 60mg) - 4-PrO-DMT sits next to psilocybin and 4-AcO-DMT as significant, fascinating, noteworthy. Its psychedelic range / footprint is large. Clean and clear on the body. Equal parts fun, serious, contemplative. With higher doses, this chemical assumes a detached, marked authority over the ego - like 4-AcO-DMT or magic mushrooms - less warm earth teacher, more intrepid alien explorer. Mixture of sedation and stimulation that doesn't strain the system for hours like LSD. Dissociative characteristics - me watching my sitting body cascade into the couch, in the 3rd person, or fish-eye type wide-angle imagery. Large range of visuals - infinite neon fractal universes a la Magic Eye.. multi-color string-like 3D projections morphing off of real world objects.. organic planes of the universe "opening" like a mouth.

During my 60mg trip, I was visited by a series of entities. Snake-like, humanoid medusas would sweep in & encircle my arms / body. This would happen suddenly, with indistinguishable auditory communication like a metallic vocoder. During my peak (1.5 - 3 hrs), I would have large, neon, geometric objects such as pyramid or square grid lattices superimposed into my environment, such as onto my coffee table. I could move my head & body around them & they would remain static, scaling with other objects in the room - like an AR headset superimposing visuals on top of your existing environment - except there was a distinct **outside will** controlling these events. I was a witness, but not in control.

There were unsettling sequences where liquid and flesh-like matter spattered around my world, along with the physical sensation of a warm bursting sensation - never painful, but surprising and uncompromising. I got tense and afraid, as I could not really control the arrival or character of these visions.

The 60mg trip contained a particularly violent, disturbing series of images that involved black, alien tentacles or mouth parts. On a subsequent 28mg trip, I briefly had these images return - they sort of "ripped" thru a hole in the center of my vision from another, less hazardous sequences of images - in a very startling and unexpected way. That visual in particular felt hostile, menacing.

This chemical seems to be able to produce a visual render of my brain's separate internal processes, with little explanation - like an accidental glimpse. Problem-solving and deep introspection is very possible - but only as the trip schedule allows. In other words, there were times where I could steer the ship - and other times where I had to hand off control. I respected its authority most of the time - except when "it" made random, chaotic decisions with no apparent moral or thematic structure. I was then left to hope "it" would go easy on me.

To contrast chemicals: 4-AcO-MET brought significant visuals , but none of 4-PrO-DMT's purpose or gravity. LSD brought a significant and powerful lens to bear - with much overlap in "otherworldly", profundity and strangeness - but it didn't carry the same personality or agenda. Magic mushrooms (4-HO-DMT) had a fleeting, curious, earthly personality.. 4-AcO-DMT had an all-encompassing universe-occupying personality.. and 4-PrO-DMT had an equally serious but colder, semi-synthetic, less empathetic, hugely impressive & remarkable spirit. All three of the 4-substituted DMT variants could be called siblings of the same family, but 4-PrO-DMT left the house first & isn't as concerned with keeping you safe.

9.8 / 10

My brief history of psychedelics: LSD (50+ times), psilocybin (~30x), DXM (~20x), 4-AcO-DMT (~20x), 4-AcO-MET (3x), 4-HO-MET (5x), 5-MeO-MiPT (30x), 4-HO-MiPT (5x), 2C-I (20+ times), 2C-E (1x), LSA (~5 times), Salvia (~3 times), MDMA (5x), N2O Nitrous combo with various ^ (approx. 1/4 of the time), Cannabis combo with various ^ (approx. 1/2 of the time)

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4-PRO-DMT

  • Product Code: 4-PRO-DMT
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